Two major focus research areas related to the design of the next generation multihop wireless networks are network lifetime extension and interference suppression. In this dissertation, these two issues are addressed.

In the area of interference suppression, a new family of projection multiuser detectors, based on a generalized, two-stage design is proposed. Projection multiuser detectors provide efficient protection against undesired interference of unknown power, while preserving simple design, with closed-form solution for error probabilities. It is shown that these detectors are linearly optimal, if the interference power is unknown.

In the area of network lifetime extension, a new approach to minimum energy routing for multihop wireless networks in Rayleigh fading channels is proposed. It is based on the concept of power combining, whereby two users transmit same signal to the destination user, emulating transmit diversity with two transmit antennas. Analytical framework for the evaluation of the benefits of power combining, in terms of the total transmit power reduction, is defined. Simulation results, which match closely the analytical results, indicate that significant improvements, in terms of transmit power reduction and network lifetime extension, are achievable. The messaging load, generated by the new scheme, is moderate, and can be further optimized.