NJIT eTD::njit-etd1999-054::Derr, Peter Haines::"A signal conditioning approach for the extraction of the oscillatory petential from the electroretinogram"

The oscillatory potential (OP), a signal component of the electroretinogram (ERG), was investigated to determine correlation of the OP and pathological conditions of the inner retina. Large transients characterize the ERG. Such transients stimulate a filter's natural response. Since these responses can co-occur with the OP, a distorted OP will be extracted. A proposed signal windowing and padding technique for conditioning the ERG signal has been implemented for the extraction of a ntnimally distorted OP.

Windowing is used to capture only the OP period. The windowed ERG signal is then signal conditioned to generate initial values for the filter's state variables. Such correct initial conditions eliminate the perturbations created from filtering the windowed ERG. OPs were successfully extracted from a database of fifty human ERGs. The extracted OPs did not display any filter-induced oscillations and did provide some indication of the retina's pathology.

Title:	A signal conditioning approach for the extraction of the oscillatory petential from the electroretinogram
Author:	Derr, Peter Haines
Document Type:	Thesis
Department:	Department of Electrical and Computer Engineering
Degree:	Master of Science
Major:	Electrical Engineering
Advisory Committee:	Meyer, Andrew Ulrich Haupt, Edward Joseph Chang, Timothy Nam Reisman, Stanley S.
Thesis Date:	1999, May
Keywords:	Eye --Movements. Electroretinography.
Availability:	Unrestricted
Abstract:	The oscillatory potential (OP), a signal component of the electroretinogram (ERG), was investigated to determine correlation of the OP and pathological conditions of the inner retina. Large transients characterize the ERG. Such transients stimulate a filter's natural response. Since these responses can co-occur with the OP, a distorted OP will be extracted. A proposed signal windowing and padding technique for conditioning the ERG signal has been implemented for the extraction of a ntnimally distorted OP. Windowing is used to capture only the OP period. The windowed ERG signal is then signal conditioned to generate initial values for the filter's state variables. Such correct initial conditions eliminate the perturbations created from filtering the windowed ERG. OPs were successfully extracted from a database of fifty human ERGs. The extracted OPs did not display any filter-induced oscillations and did provide some indication of the retina's pathology.
Complete Thesis:	njit-etd1999-054 (133 pages ~ 11,054 KB pdf)
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